Process Development Engineer II, Upstream Development - Gene Therapy
Build our future together:
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At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a highly motivated Process Development Engineer II to join our Preclinical Manufacturing and Process Development (PMPD) group, responsible for upstream development efforts to support manufacturing process development functions. In this role, you will work as part of a multi-functional team to provide Adeno-Associated Virus (AAV) manufacturing processes and products with the aim of providing treatment to unmet medical needs through gene therapy. This is a growth opportunity that combines the excitement and opportunity of a start-up with the security and institutional knowledge gained from working for a larger firm. You will have the unique opportunity to work on production processes across a wide range of scales from 200 mL to 500 L, and support programs across the development lifecycle, from research through clinical development, regulatory filing, and approval.
When & where:
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- Shift Requirements: Full-time
- Location: On-site in Tarrytown, NY
- Other requirements: Job will periodically require short duration physical exertions, including light-medium weight lifting
Discover your role:
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- Design optimized, well-characterized, and robust seed train and bioreactor processes for upstream viral vector production in suspension cell lines, suitable for future GMP clinical and commercial production
- Lead the design and execution of studies to optimize transfection, bioreactor, and scale-up parameters for viral production using multivariate design of experiment approaches
- Serve as an upstream subject matter expert and lead technology transfer to clinical manufacturing for future gene therapy programs
- Conduct technology development studies aimed at enhancing process understanding and improving viral vector production, includ...
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