Scientist, Discovery Biology

Denali Therapeutics Inc. is a biotechnology company pioneering a new class of biotherapeutics designed to cross the blood-brain barrier (BBB) using its proprietary TransportVehicle™ platform. With the first FDA-approved biologic specifically designed to cross the BBB, a clinically validated delivery platform and a growing portfolio of therapeutic candidates across all stages of development, we are advancing toward our goal of delivering effective medicines to transform the lives of people living with neurodegenerative diseases, lysosomal storage disorders and other serious diseases.

We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.

Advances Denali’s oligonucleotide therapeutic pipeline by generating the in vivo and ex vivo evidence that guides candidate selection. Applies animal models, molecular and cellular assays, and pharmacokinetic and pharmacodynamic (PK/PD) studies to validate targets, identify biomarkers, and inform therapeutic development. Partners with Preclinical Translational Sciences, Developmental Sciences, Safety, and drug metabolism and pharmacokinetics (DMPK) scien...

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